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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
33.33
Human Site:
Y375
Identified Species:
66.67
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
Y375
P
D
E
E
V
V
V
Y
G
I
P
Y
L
Q
N
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
Y377
P
D
E
E
V
V
V
Y
G
I
P
Y
L
Q
N
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
Y347
N
E
E
D
V
V
V
Y
A
P
E
Y
L
T
K
Dog
Lupus familis
XP_546737
807
92419
Y403
P
D
E
E
V
V
V
Y
G
I
P
Y
L
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
Y361
P
D
E
E
V
V
V
Y
G
I
P
Y
L
E
N
Rat
Rattus norvegicus
P0C1T0
774
89178
Y370
P
N
E
E
V
V
V
Y
G
I
P
Y
L
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
Y345
P
E
E
E
V
V
V
Y
G
M
P
Y
L
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
Y351
S
D
E
P
I
V
I
Y
C
S
P
Y
L
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
Y448
E
D
E
P
L
V
T
Y
G
L
H
Y
L
T
E
Honey Bee
Apis mellifera
XP_392502
776
89056
Y375
E
E
E
P
I
V
A
Y
A
M
P
Y
F
M
Q
Nematode Worm
Caenorhab. elegans
O16796
848
97043
C445
N
E
T
E
I
I
I
C
E
I
E
Y
L
Q
H
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
K363
D
D
E
F
I
N
N
K
E
P
E
F
V
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
46.6
100
N.A.
93.3
86.6
N.A.
N.A.
80
N.A.
46.6
N.A.
46.6
33.3
33.3
13.3
P-Site Similarity:
100
100
60
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
66.6
N.A.
60
53.3
66.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% C
% Asp:
9
59
0
9
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
17
34
92
59
0
0
0
0
17
0
25
0
0
25
17
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
0
0
0
34
9
17
0
0
50
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
17
% K
% Leu:
0
0
0
0
9
0
0
0
0
9
0
0
84
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
17
0
0
0
9
0
% M
% Asn:
17
9
0
0
0
9
9
0
0
0
0
0
0
0
42
% N
% Pro:
50
0
0
25
0
0
0
0
0
17
67
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
9
0
0
0
0
0
0
25
0
% T
% Val:
0
0
0
0
59
84
59
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
92
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _